Acute Myelogenous Leukemia (AML) and Benzene Exposure

Toxic exposureAcute myelogenous leukemia (AML) is the most common type of acute leukemia, and it can be caused by benzene exposure. There are more than 11,900 new cases in the United States annually; the average age at diagnosis is 65 years old. It also appears to be slightly more prevalent in males than in females. Common symptoms of AML include fatigue, bruising or bleeding, fever, and infection.  If you suspect that your AML is related to benzene exposure, you should contact a chemical exposure attorney to discuss the legal options available to you.

Call us at 1-888-554-2889 to speak to a benzene toxic exposure lawyer personally. We offer:

  • A free, no-obligation case evaluation with a benzene poisoning lawyer
  • No fee unless we win your case
  • Flexible appointments
  • Home and hospital visits


What is AML?

Acute myelogenous leukemia (AML), also known as acute myeloblastic leukemia, acute myeloid leukemia, acute granulocytic leukemia or acute nonlymphocytic leukemia, is a disease in which the bone marrow makes stem cells, or blasts, that should develop into lymphoid cells that become white blood cells, or a myeloid cells that can become either oxygen-carrying red blood cells, or disease-fighting white blood cells, or platelets that aid in the formation of blood clots that stop bleeding. However, the blasts that are produced are abnormal, so they cannot mature as they should. Instead, they remain as they are, crowding out normal red blood cells, white blood cells and platelets. These abnormal cells are called leukemia cells.


Benzene Exposure and AML

One of the most frequently cited causes for AML is benzene exposure, which is far more common than most people think. In an August 2007 Public Health Statement on benzene, the Agency for Toxic Substances and Disease Registry, a division of the Centers for Disease Control and Prevention (CDC) said:

“The Environmental Protection Agency (EPA) identifies the most serious hazardous waste sites in the nation. These sites are then placed on the National Priorities List (NPL) and are targeted for long-term federal clean-up activities. Benzene has been found in at least 1,000 of the 1,684 current or former NPL sites. Although the total number of NPL sites evaluated for this substance is not known, the possibility exists that the number of sites at which benzene is found may increase in the future as more sites are evaluated.”

The agency noted that other sources of benzene exposure are tobacco smoke, automobile service stations, exhaust from motor vehicles, industrial emissions, and vapors from products that contain benzene, such as glues, paints, furniture wax, and detergents.


Benzene AML Clinical Trials

Clinical studies have been conducted to examine the association between benzene exposure and AML:

  • Benzene and lymphohematopoietic malignancies in humans, published August 2004 in the Journal of Industrial Medicine, researchers found that there was an increase in risk for acute myeloid leukemia over a broad dose range of benzene exposure.
  • Review of the literature on benzene exposure and leukemia subtypes, published May 30, 2005 in Chemico-Biological Interactions, researchers noted that, “High and significant acute myeloid leukemia risks with positive dose response relationships were identified across study designs, particularly in the “well-conducted” cohort studies and especially in more highly exposed workers in rubber, shoe, and paint industries.”
  • Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis, published June 28, 2010 in Environmental Health, researchers observed that benzene exposure increased risk for leukemia in general, and for the subset of AML


Contact a Benzene Exposure Lawyer

If you or someone you love has developed acute myelogenous leukemia (AML) after benzene exposure, you may be eligible to file a lawsuit to collect compensation.  Our benzene exposure & poisoning lawyers are experienced in toxic exposure litigation, and can help get injured workers and their families the compensation they deserve.  Contact us today for a free consultation with a benzene exposure lawyer.


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